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2-Thiazolecarboxaldehyde

Catalog No.
C15-1200-129
Manufacturer No.
422460-1G
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
GR
Price: $169.97
List Price: $188.86

2-Thiazolecarboxaldehyde is a thiazole aldehyde derivative. It undergoes Baylis–Hillman reaction with methyl acrylate catalyzed by DABCO (1,4-diazabicyclo[2.

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General description

2-Thiazolecarboxaldehyde is a thiazole aldehyde derivative. It undergoes Baylis–Hillman reaction with methyl acrylate catalyzed by DABCO (1,4-diazabicyclo[2.2.2]octane). The reaction mechanism has been studied by electrospray ionization mass spectrometry (ESI-MS).

Application

2-Thiazolecarboxaldehyde may be used as a reactant in the following syntheses:

  • Benzothiazine N-acylhydrazones, having potential antinociceptive and anti-inflammatory activity.
  • Thiazole-2-yl-(amino)methylphosphonate diethyl esters.
  • Imino ester by reacting with L-leucine t-butyl ester hydrochloride.

Useful building block for taxane analogs.

UPC:
51303300
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
422460-1G


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