Application
This ′trimethyl lock′ derivative is activated with a succinimidyl ester for modification of amine containing compounds and biomolecules. After modification of your amine of interest, your now ′masked′ molecule can be released by cleavage of the ester, which can be achieved by cellular esterases. This triggers a rapid lactonization reaction of the ′trimethyl lock′ to regenerate your original amine-containing molecule. This approach has been applied to release of fluorophores, peptides, nucleic acids as well as small molecule drugs.
Molecular Weight: 361.39. Empirical Formula: C19H23NO6. Quality Level: 100. Assay: 95%. form: solid. mp: 107-112 . °C. storage temp.: 2-8°C. SMILES string: CC(: O)Oc1cc(C)cc(C)c1C(C)(C)CC(: O)ON2C(: O)CCC2: O. InChI: 1S/C19H23NO6/c1-11-8-12(2)18(14(9-11)25-13(3)21)19(4,5)10-17(24)26-20-15(22)6-7-16(20)23/h8-9H,6-7,10H2,1-5H3. InChI key: KMNOKEFBKJGRFL-UHFFFAOYSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H302. Hazard Classifications: Acute Tox. 4 Oral. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51273105
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 776181-250MG