3-NITROPROPIONIC ACID (C15-1880-000)

Catalog No.: C15-1880-000
Mfr. No.: N5636-10G
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: GM

Price: $1,176.92

List Price: $1,307.69

Application 3-Nitropropionic acid has been used: to generate multiple system atropy-parkinsoniam (MSA-P) model in rat to evaluate its effect on embryonic striatal and mesencephalic grafts to inject into the nigrostriatal dopaminergic pathway

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Description
Specifications

Application

3-Nitropropionic acid has been used:

to generate multiple system atropy-parkinsoniam (MSA-P) model in rat to evaluate its effect on embryonic striatal and mesencephalic grafts
to inject into the nigrostriatal dopaminergic pathway in rats in order to examine its specific effects on the dopamine system
as succinate dehydrogenase (SDH) inhibitor for LUHMES neurons and cell lines

Biochem/physiol Actions

Administering 3-nitropropionic acid (3-NP) to the inner ear can stimulate sensorineural hearing loss. It serves as an irreversible inhibitor of mitochondrial complex II.

Excitotoxin shown to cause brain lesions similar to those of Huntington′s disease.

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UPC:: 51142425
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: Yes
MPN:: N5636-10G
CAS:: 504-88-1

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