4,6-Dioxoheptanoic acid (C15-1245-439)

Sigma-Aldrich

Catalog No.: C15-1245-439
Manufacturer No.: D1415-100MG
Manufacturer Name: Sigma-Aldrich
Quantity: 100
Unit of Measure: MG

Price: $536.57

List Price: $596.19

Application 4,6-Dioxoheptanoic acid has been used: as component of dendritic cell conditioning medium and in the inhibition of ALA dehydratase (ALAD) in dendritic cells(50) as an inhibitor of heme biosynthesis in human mononuclear cells(51) and

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Description
Specifications

Application

4,6-Dioxoheptanoic acid has been used:

as component of dendritic cell conditioning medium and in the inhibition of ALA dehydratase (ALAD) in dendritic cells(50)
as an inhibitor of heme biosynthesis in human mononuclear cells(51) and HeLa cells(52)
as a standard for the quantification of succinylacetone from Plasmodium falciparum cultures(53)

Biochem/physiol Actions

4,6-Dioxoheptanoic acid is an inhibitor of heme biosynthesis. It is a catabolic byproduct of tyrosine breakdown and inhibits δ-aminolevulinic acid (ALA) dehydratase enzyme. It is a potential marker for detecting tyrosinemia type I and is measured in dried blood spot of new borns.

An inhibitor of heme biosynthesis

UPC:: 12352100
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: D1415-100MG

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