4-Bromo-calcium Ionophore A23187 (C15-1279-579)

Catalog No.: C15-1279-579
Manufacturer No.: B7272-1MG
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: MG

Price: $514.29

List Price: $571.43

Application 4-Bromo-calcium Ionophore A23187 has been used for the activation of Ca 2+ /calmodulin kinase II (CaMKII) in HeLa cell line. It has also been used as a calcium mobilizer to investigate its effect on superoxide dismutase 1 (SOD1)

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Description
Specifications

Application

4-Bromo-calcium Ionophore A23187 has been used for the activation of Ca²⁺/calmodulin kinase II (CaMKII) in HeLa cell line. It has also been used as a calcium mobilizer to investigate its effect on superoxide dismutase 1 (SOD1) aggregates in VSC 4.1 cells.

Nonfluorescent Ca²⁺ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca²⁺ with fluorescent probes.

Biochem/physiol Actions

4-Bromo-calcium Ionophore A23187 is a modulator of apoptosis. It inhibits apoptosis in a concentration dependent manner in neutrophils which are aging in vitro and increases the intracellular Ca²⁺ levels.

Other Notes

Analog of calcium ionophore A23187

UPC:: 41116113
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: B7272-1MG

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