4-Bromomethyl-3-nitrobenzoic acid

General description

4-Bromomethyl-3-nitrobenzoic acid (BNBA) is a benzoic acid derivative. It has been synthesized by the nitration of 4-bromomethylbenzoic acid using fuming nitric acid. It participates in the synthesis of 3,4-dihydro-2(1H)-quinazolinones and 3,4-dihydro-1H-quinazolin-2-thiones.

Application

4-Bromomethyl-3-nitrobenzoic acid may be used in the following studies:

• As a reactant in the synthesis of 4-bromomethyl-3-nitrobenzoic acid succinimide ester (BNBA-SE).
• As a reactant in the synthesis of 4-(2-hydroxyethylmercaptylmethyl)-3-nitrobenzoic acid.
• As a reactant in the synthesis of decyl 4-(bromomethyl)-3-nitrobenzoate.
• As a reactant in the synthesis of 4-((2-(hydroxymethyl)phenylamino)methyl)-3-nitrobenzoic acid.
• As a thiol photo-deprotection reagent.
• As a UV-cleavable reagent to functionalize polyacrylamide acryl hydrate (PAAH).
• As a photocleavable linker to form localized photoinversion of surface charges inside the colloidal crystal.
• As a starting material in the synthesis of 2H-indazole based library using parallel solution-phase methods.
• As a reactant in the synthesis of (N-allyloxycarbonyl)-5-aminopent-1-yl 4-bromomethyl-3-nitrobenzoate.