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4-Cyanophenylboronic acid (C15-1209-976)

Sigma-Aldrich

Catalog No.
C15-1209-976
Manufacturer No.
521418-10G
Manufacturer Name
Sigma-Aldrich
Quantity
10
Unit of Measure
GR
Price: $589.54
List Price: $655.05

Application 4-Cyanophenylboronic acid can be used as a reactant in: Palladium-catalyzed Suzuki-Miyaura cross-coupling in water. Ruthenium catalyzed direct arylation of benzylic sp 3 carbons of acyclic amines with arylboronates.

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Application

4-Cyanophenylboronic acid can be used as a reactant in:

  • Palladium-catalyzed Suzuki-Miyaura cross-coupling in water.
  • Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates.
  • Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids.
  • Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters.
  • Phosphine-free Suzuki-Miyaura cross-coupling.
  • Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates.
  • Chan-Lam-type Cu-catalyzed S-arylation of thiols.
  • Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with copper catalysis.
  • Metal-free biaryl coupling reaction in the presence of dimethyl carbonate as a solvent.
  • Suzuki-type cross-coupling reaction with pentavalent triarylantimony diacetates in the absence of a base.

It can also be used to prepare:
  • Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents.
  • Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark.
  • Antimalarial compounds via Suzuki cross-coupling.
  • Deoxyuridine derivatives.

Reactant involved in:

  • Oxidative hydroxylation
  • Trifluoromethylation
  • 1,4-Addition reactions

Precursor in the synthesis of inhibitors such as:
  • Tpl2 kinase inhibitors
  • P2X7 antagonists used in the treatment of pain

Other Notes

Contains varying amounts of anhydride

UPC:
41116134
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
521418-10G


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