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4-fluoro-1-indanone (c15-1620-277)

W-7 HYDROCHLORIDE 1PC X 10MG (C005B-246277)

Catalog No.
C005B-246277
Mfr. No.
681636-1MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
MG
Price: $337.94
List Price: $375.49

General description A cell-permeable and reversible calmodulin antagonist that inhibits Ca 2+ -calmodulin-dependent phosphodiesterase (IC 50 = 68 µ:M) and myosin light chain kinase (IC 50 = 58 µ:M). A cell-permeable and reversible

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General description

A cell-permeable and reversible calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 68 µM) and myosin light chain kinase (IC50 = 58 µM).

A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 58 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 68 µM).

Biochem/physiol Actions

Target IC50: 58 µM, 68 µM, against myosin light chain kinase and Ca2+-calmodulin-dependent phosphodiesterase

Warning

Toxicity: Standard Handling (A)

Analysis Note

single spot by TLC

Other Notes

Hidaka, H., and Tanaka, T. 1983. Methods Enzymol. 102, 185.
Tanaka, T., et al. 1983. Pharmacol.26, 249.
Tanaka, T., and Hidaka, H. 1980. J. Biol. Chem. 255, 11078.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:
51263406
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
681636-1MG
CAS:
88519-57-7

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