4-Methylumbelliferyl α-L-iduronide (free acid) (C09-0961-483)

4-Methylumbelliferyl α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase. This is found in cell lysosomes, which is involved in the degradation of glycosaminoglycans. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). This 4-Methylumbelliferyl α-L-iduronide form is the free acid, which offers a considerable weight for weight advantage over the 4-MU iduronide salt in terms of its application dose.|For further studies, use α-L-iduronidase gene silencing|siRNA and shRNA|reagents and α-L-iduronidase gene editing|CRISPR|knockout and activation products. Molecular Formula: C16H16O9 Molecular Weight: 352.29 EC Number: 266-527-5 PubChem CID: 128746 Isomeric SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](O3)C(=O)O)O)O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/M331620-SCI_1bf88513e6d8ca760a50cb1c6e9a5429.pdf