4-oxo 2-Nonenal-d3 (4-ONE-d3) contains three deuterium atoms at the terminal methyl position. It is used for an internal standard for the quantification of 4-ONE by GC- or LC-mass spectrometry (MS). 4-ONE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. It exhibits various biological activities such as cytotoxicity, genotoxicity, growth inhibiting activity, chemotactic activity and has been widely used as a marker of lipid peroxidation . 4-ONE is a recently identified product of lipid peroxidation. It actively modifies histidine and lysine residues on proteins and causes protein cross-linking. 4-ONE also modifies 2'-deoxy guanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis. Specification: A solution in methyl acetate Molecular Formula: C9H11D3O2 Molecular Weight: 157.2 PubChem CID: 53381675
- UPC:
- 12352002
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- O358628-100μg
- CAS:
- 1313400-91-7
- Physical Hazards:
- Flammable Liquid
- Product Size:
- 100μg
