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5-chloro-8-hydroxy-7-iodoquinoline (c09-0823-767)

5-Chloro-8-hydroxy-7-iodoquinoline (C09-0823-767)

Aladdin

Catalog No.
C09-0823-767
Manufacturer No.
C421179-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $114.38
List Price: $127.09

Clioquinol is a member of the hydroxyquinoline family which inhibits certain enzymes related to DNA replication. Clioquinol is a metal chelating ligand which displays protective effects in various neurodegenerative states as well as being a

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Clioquinol is a member of the hydroxyquinoline family which inhibits certain enzymes related to DNA replication. Clioquinol is a metal chelating ligand which displays protective effects in various neurodegenerative states as well as being a component in antifungal and antiprotozoal agents. It has been shown to modulate amyloid beta-peptide accumulation via upregulation of metalloprotease activity. When co-administered with vitamin B12, Clioquinol rescues lead-induced impairments of synaptic plasticity in an animal models. In recent animal studies Clioquinol has shown to reverse the progression of Parkinson's, Alzheimer's, and Huntington's diseases. Clioquinol has been observed to induce apoptosis in human cancer cell lines by generating free zinc in lysosomes.A metal chelating ligand that inhibits certain enzymes related to DNA replication. Specification: 10mM in DMSO Molecular Formula: C9H5ClINO Molecular Weight: 305.5 EC Number: 204-984-4 PubChem CID: 2788 Isomeric SMILES: C1=CC2=C(C(=C(C=C2Cl)I)O)N=C1 Beilstein Registry Number: 153637
UPC:
12352005
Condition:
New
Availability:
2 weeks
Weight:
0.85 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
C421179-1ml
CAS:
130-26-7
Product Size:
1ml


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