(±)5-iPF2α-VI-d11 (C09-0926-995)

5-iPF2α-VI-d11 contains 11 deuterium atoms and is intended for use as an internal standard for quantification of 5-iPF2α-VI by GC- or LC-mass spectrometry. Isoprostanes are prostaglandin-like products of free-radical induced lipid peroxidation. iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes that can be formed from arachidonic acid. As of now, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III) . However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers that form in natural conditions of oxidative stress, including iPF2α-VI of the type-VI isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones which facilitate their extraction and purification from biological samples. Specification: A solution in ethanol Molecular Formula: C20H23D11O5 Molecular Weight: 365.55 PubChem CID: 42607310 Isomeric SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])/C=C/C[C@H]1[C@@H](C[C@@H]([C@H]1/C=C/C(CCCC(=O)O)O)O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/I345902-SCI_b90e3d6670ec7520f87e813e4ac3afe0.pdf