Application 5-Pregnen-3β:-ol-20-one-16α:-carbonitrile has been used: in the induction of cytochrome P450 as pregnane X receptor (PXR) activator in human liver cell lines. Biochem/physiol Actions Pregnenolone-16a-carbonitrile
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5-Pregnen-3β-ol-20-one-16α-carbonitrile has been used:
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
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