5A-PREGNAN-3A-OL-11 20-DIONE

Catalog No.: C005B-439140
Mfr. No.: P5052-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $451.39

List Price: $501.55

Biochem/physiol Actions Synthetic steroid compound alphaxalone (AFX) - 5α:-Pregnan-3α:-ol-11,20-dione- is a neurosteroid that directly activates and potentiates GABA A receptor-activated membrane current (IGABA). It acts as a positive

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Biochem/physiol Actions

Synthetic steroid compound alphaxalone (AFX) - 5α-Pregnan-3α-ol-11,20-dione- is a neurosteroid that directly activates and potentiates GABA_A receptor-activated membrane current (IGABA). It acts as a positive allosteric modulator of the GABA_A receptor; anesthetic. The alpha subunit subtype of GABA_A determines the efficacy, but not the potency, of AFX neuroactive steroid to potentiate IGABA.

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UPC:: 51182056
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: Yes
MPN:: P5052-10MG
CAS:: 23930-19-0
Temperature Control Device:: Yes

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