(5E,9E,13E)-Teprenone (C007B-430932)

(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress.In Vitro(5E,9E,13E)-Teprenone might transiently activate the transcription of HSP70 gene. The heat shock element–binding activity reflects the activation of heat shock factor 1 in response to (5E,9E,13E)-Teprenone. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In Vivo(5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wister strain rats (≈250 g) Dosage: 200 mg/kg Administration: Oral administration Result: Caused accumulations of all of HSP90, HSP70, HSC70 and HSP60 within 60 minutes.Form:Liquid. Specification: 0.99 Molecular Formula: C23H38O Molecular Weight: 330.55