6,7-dihydroxy Bergamottin-1 mg

Catalog No.: C003B-360330
Mfr. No.: 10009598-1
Mfr. Name: Cayman Chemical Company
Qty/UOM: 1
UOM: EA

Price: $76.14

List Price: $84.59

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Description
Specifications

6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 µM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6β-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by cytochrome P450 enzymes of the CYP3A subfamily results in a substantial increase in plasma concentration of these agents. However, giving a patient grapefruit juice or just 6,7-DHB could be advantageous in cases where a drug is metabolized too quickly by CYP3A4.

UPC:: 51182069
Condition:: New
Availability:: 3 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: 10009598-1
CAS:: 145414-76-2

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