6-Chloropurine (C15-1285-688)

Catalog No.: C15-1285-688
Manufacturer No.: 511617-5G
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: GR

Price: $61.06

List Price: $67.84

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Description
Specifications

General description

6-Chloropurine (6-CIPH), a 6-substituted purine derivative, is an antileukemic drug. It can be prepared by the chlorination of hypoxanthine with phosphorus oxychloride in the presence of dimethylaniline. The NMR-based conformational analysis of the products formed during the reaction of 6-CIPH with 3,4-di-O-acetyl-D-xylal and 3,4-di-O-acetyl-L-arabinal have been reported. 6-CIPH can undergo palladium-catalyzed cross coupling with organostannanes at 6-position to form the corresponding arylated or alkylated products.

Application

6-Chloropurine may be used:

To prepare purine via catalytic dehydrogenation.
To prepare 9-alkylated adenines via Mitsunobu reaction with various alcohols.
As a starting material to synthesize dihydroisoxazole 6-chloropurine.

UPC:: 51412502
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: 511617-5G

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