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6-hydroxyflavanone

6-HYDROXYFLAVANONE 99%

Catalog No.
C005B-039616
Mfr. No.
419796-1G
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
GR
Price: $126.21
List Price: $140.24

6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described.

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General description

6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enanti­omers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio. It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis.

Application

6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells.

UPC:
51303200
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
419796-1G
CAS:
4250-77-5

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