DMNB (4,5-dimethoxy-2-nitrobenzaldehyde) is a cell-permeable vanillin derivative and potent inhibitor of DNA-PK (IC50 = 15 μM). DMNB is shown in experiments to increase DR4/DR5 mRNA levels and their surface expression and decrease c-FLIP mRNA levels in K56. DMNB is also an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair. Specification: ≥85.0%(GC) MDL Number: MFCD00007134 Molecular Formula: C9H9NO5 Molecular Weight: 211.17 EC Number: 243-762-1 PubChem CID: 88505 Isomeric SMILES: COC1=C(C=C(C(=C1)C=O)[N+](=O)[O-])OC Beilstein Registry Number: 8262 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/N138447-SCI_e1fad9d777b436f3e945f58625acdd39.pdf
- UPC:
- 51242309
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 4.61 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N138447-5g
- CAS:
- 20357-25-9
- Product Size:
- 5g
