Application
7-Amino-4-methylcoumarin has been used:
- to determine cathepsin B like- activity
- as a substrate for leucine aminopeptidase (LAP)
- in chymotryptic assay
- as a standard to detect the activation of caspase-3 during
- sanguinarine-induced damage
- protection by human DEAD-box DDX3
Used as matrix for analysis of monosulfated disaccharides and as a co-matrix with 6-aza-2-thiothymidine for sulfated neutral and sialylated tri-and tetrasaccharides.
Biochem/physiol Actions
7-Amino-4-methylcoumarin is a coumarin derivative, which serves as a fluorescence reference standard to screen protease inhibitors.
Preparation Note
Soluble in DMSO (10 mg/mL), DMF, and acetone (10 mg/mL).
Other Notes
Reagent for preparing new fluorogenic AMC-based substrates for cystine aminopeptidase (and other hydrolases); used as reference compound in the enzyme assay.
- UPC:
- 51473404
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A9891-250MG
