7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H|2|S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H|2|S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with λex = 365 nm and λem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine β-synthase (CBS), cystathionine γ-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine β-synthase (CBS) inhibitors and activators.
Specification: ≥98%
Molecular Formula: C10H7N3O2
Molecular Weight: 201.18
PubChem CID: 53872933
Isomeric SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)N=[N+]=[N-]
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A331202-SCI_5ca470ff75b723df781127dc62f6c0fc.pdf
- UPC:
- 51131651
- Condition:
- New
- Availability:
- 1 day
- Weight:
- 0.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A331202-5mg
- CAS:
- 95633-27-5
- Product Size:
- 5mg
- Precautionary Statement Codes:
- P280:P271:P264:P261
