7-Ethyl-10-hydroxycamptothecin (C15-1285-342)

Catalog No.: C15-1285-342
Manufacturer No.: H0165-50MG
Manufacturer Name: Sigma-Aldrich
Quantity: 50
Unit of Measure: MG

Price: $1,224.00

List Price: $1,360.00

Application 7-Ethyl-10-hydroxycamptothecin has been used: to inhibit enterovirus 71 (EV71) (H) infection to screen the chemosensitivity of pancreatic adenocarcinoma cells as a chemical to study its ability to reverse multidrug resistance (MDR), due

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account.

Current Stock:

Quantity:

Adding to cart… The item has been added

Description
Specifications

Application

7-Ethyl-10-hydroxycamptothecin has been used:

to inhibit enterovirus 71 (EV71) (H) infection
to screen the chemosensitivity of pancreatic adenocarcinoma cells
as a chemical to study its ability to reverse multidrug resistance (MDR), due to ATP binding cassette (ABC) transporters

Biochem/physiol Actions

Active metabolite of irinotecan. Inhibitor of topoisomerase I.. Gene expression analysis of colon cancer cell lines treated with SN-38 showed differential effects: the majority of affected genes were down-regulated (including, most strongly, genes related to receptor and kinase activity, signal transduction, apoptosis, RNA processing, protein metabolism and transport, cell cycle and transcription. Some of the up-regulated genes were involved in apoptosis, transcription, development and differentiation.

UPC:: 51281718
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: H0165-50MG

Cenmed Satisfaction Guarantee

At Cenmed, your confidence and satisfaction are paramount. We guarantee the quality and reliability of our extensive range of clinical and laboratory supplies. If you're not completely satisfied with your purchase, we offer a straightforward return process and dedicated support to resolve your concerns promptly. Our commitment ensures that you can order with confidence, knowing that Cenmed is dedicated to superior service and customer satisfaction. Trust us to meet your needs with every order, backed by our promise of excellence. Learn more in Help & FAQs.

"Cenmed provides me access to the same products/services normally reserved for much larger labs than mine. I was presently surprised by their product offering."