Amino Acid Sequence
MCA-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-DNP-Lys-Arg-Arg-NH2
Application
7-Methoxycoumarin-4-acetyl-[Asn⁶⁷⁰,Leu⁶⁷¹]-Amyloid β has been used as a fluorogenic substrate to measure β-secretase activity.
Biochem/physiol Actions
Fluorescent peptide substrate containing the ′Swedish′ Lys-Met/Asn-Leu mutation of the amyloid presursor protein (APP) β-secretase cleavage site. May be used for assaying β-secretase-like activity of thimet oligopeptidase (TOP), EC 3.4.24.15.
Molecular Weight: 2001.08. Empirical Formula: C86H125N27O29. Quality Level: 100. Assay: ≥. 90% (HPLC). form: powder. UniProt accession no.: P05067. storage temp.: −. 20°C. Gene Information: human ... APP(351). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).- UPC:
- 51143904
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A1472-1MG