740 Y-P TFA (C007B-317014)

Information740 Y-P (PDGFR 740Y-P) 740 Y-P (PDGFR 740Y-P, 740YPDGFR) is cell-permeable phosphopeptide activator of PI3K .TargetsPI3KIn vitroThe PDGFR 740Y-P peptide stimulates a mitogenic response in muscle cells. The ability of the 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell permeable SH2 domain binding peptides. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose dependent and does not require insulin.Cell Research(from reference)Cell lines：NIH 3T3 cells Concentrations：50 μg/ml Incubation Time：2 h. Specification: 0.98 Molecular Formula: C141H222N43O39PS3(free basis) Molecular Weight: 3270.7(free basis)