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8-bromoadenosine 3',5'-cyclic monophosphate sodium salt (c15-1280-496)

8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt (C15-1280-496)

Catalog No.
C15-1280-496
Manufacturer No.
B7880-25MG
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
MG
Price: $317.14
List Price: $352.38

8-Bromoadenosine 3′:5′-cyclic monophosphate is a brominated cyclic mononucleotide. Application 8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt has been used: to study its effect on fas and caspase-3 mRNA expression

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General description

8-Bromoadenosine 3′:5′-cyclic monophosphate is a brominated cyclic mononucleotide.

Application

8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt has been used:

  • to study its effect on fas and caspase-3 mRNA expression and on P4 production in bovine mid luteal cell culture
  • used to treat choriocarcinoma BeWo cell line and study its effect on cell viability, apoptosis and morphological changes in the nuclei
  • in superfusion medium for head kidneys stimulation

Biochem/physiol Actions

Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Other Notes

Membrane-permeable cAMP analog.

Caution

Sensitive to light and moisture.

UPC:
51393605
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
B7880-25MG


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