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8-iso-15-keto Prostaglandin F2a-1 mg

Catalog No.
C08-0329-797
Manufacturer No.
16390-1
Manufacturer Name
Cayman Chemical Company
Quantity
1
Unit of Measure
EA
Price: $319.99
List Price: $355.54
*Additional Hazmat Fee will apply

8-iso-15-keto PGF2&alpha is a metabolite of the isoprostane 8-iso PGF2&alpha in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2&alpha) is a prostaglandin-like product of non-specific lipid peroxidation.

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8-iso-15-keto PGF2α is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2α was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2α. 8-iso -15-keto PGF2α is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.
UPC:
12350000
Condition:
New
Availability:
3 Days
Weight:
1.00 Ounces
HazMatClass:
Yes
WeightUOM:
LB
MPN:
16390-1


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