9(S)-HODE (C005B-313304)

Catalog No.: C005B-313304
Mfr. No.: SML0503-500UG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: EA

Price: $1,191.89

List Price: $1,324.32

Biochem/physiol Actions 9(S)-HODE is produced by the lipoxygenation of linoleic acid. It is a major component of plasma oxidized low-density lipoprotein.

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Biochem/physiol Actions

9(S)-HODE is produced by the lipoxygenation of linoleic acid. It is a major component of plasma oxidized low-density lipoprotein. 9-HODE has been shown to stimulate cell proliferation and and extracellular matrix synthesis in human mesangial cells via PPARgamma. Pro-inflammatory effects of 9-HODE, acting through the receptor GPR132, can contribute to atherosclerosis progression. 9-HODE has also been shown to activate spinal TRPV1, leading to inflammatory hyperalgesia.

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UPC:: 51321709
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0503-500UG
CAS:: 73543-67-6
Temperature Control Device:: Yes

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