Application
A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.
Biochem/physiol Actions
A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.
Features and Benefits
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Molecular Weight: 342.61 (anhydrous basis). Empirical Formula: C13H9Cl2N5·HCl · xH2O. Quality Level: 100. Assay: ≥. 98% (HPLC). form: powder. storage condition: desiccated. color: white to beige. solubility: DMSO: 20 . mg/mL, clear. originator: Abbott. storage temp.: 2-8°C. SMILES string: O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3. InChI: 1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9. . /h1-7H,8H2. 1H. 1H2. InChI key: ZHFJJBAKSROKNO-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51413107
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A9736-25MG