A BETA-METHYLENE ATP 1PC X 5MG

Sigma-Aldrich

Catalog No.: C15-1201-360
Manufacturer No.: 5054190001
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Price: $456.69

List Price: $507.43

A metabolically stable and selective P2X purinergic receptor agonist (pEC 50 = 5.81) that is shown to be more potent than ATP.

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Description
Specifications

General description

A metabolically stable and selective P2X purinergic receptor agonist (pEC₅₀ = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1 mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200 nM to 4 µM) that reaches a peak within 2-3 min after application and then decays to a steady level.

Biochem/physiol Actions

Primary Target
P2X

Reversible: yes

Warning

Toxicity: Standard Handling (A)

Other Notes

Sawyer, G.W., et al. 2000. Br. J. Pharmacol.129, 1458.
Komori, S., et al. 1988. Br. J. Pharmacol.94, 9.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:: 12352200
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: 5054190001

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