a3á2, a3á4, a4á2 nAChR antagonist and indirect DA and NE reu (C08-0489-775)

Catalog No.: C08-0489-775
Manufacturer No.: B8363-1 g
Manufacturer Name: LKT Laboratories, Inc
Quantity: 1
Unit of Measure: EA

Price: $1,288.56

List Price: $1,431.73

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Description
Specifications

Bupropion is an antidepressant that is also commonly used as a smoking cessation aid. This compound has additional therapeutic potential, as it promotes modest weight loss, shows efficacy as an ADHD treatment, and may also be an effective treatment for neuropathic pain. Bupropion is a DA and NE reuptake inhibitor, decreasing the firing rate of NE neurons due to activation of their inhibitory somatodendritic a2-adrenoreceptors by circulating NE; bupropion’s effects on NE reuptake are somewhat stronger than its effects on DA reuptake. Additionally, bupropion is a noncompetitive antagonist at a3ß2, a3ß4, a4ß2 nicotinic acetylcholine receptors (nAChRs), decreasing the probability of channel opening in closed nAChRs and accelerating desensitization in open nAChRs. Grade: ≥98%

UPC:: 41122409
Condition:: New
Availability:: 3 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: B8363-1 g
CAS:: 31677-93-7

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