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ABARELIX ACETATE (C005B-309877)

Catalog No.
C005B-309877
Mfr. No.
SML2919-25MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
25
UOM
MG
Price: $589.40
List Price: $654.89

Biochem/physiol Actions Abarelix (PPI-149) is a gonadotropin releasing hormone (GnRH)/luteinizing hormone releasing hormone (LHRH) receptor (GnRHR, LHRHR) antagonist with low histamine release induction propensity (EC 50 = 100 μ:g/mL: rat

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Biochem/physiol Actions

Abarelix (PPI-149) is a gonadotropin releasing hormone (GnRH)/luteinizing hormone releasing hormone (LHRH) receptor (GnRHR, LHRHR) antagonist with low histamine release induction propensity (EC50 = 100 μg/mL; rat mast cells). Abarelix exhibits good in vivo efficacy via iv. or sc. in suppressing LH levels in castrated male rats (plasma LH = 12/1.2/0.9/1.2 ng/mL 6 hrs post 0/12.5/50/200 μg/kg in 5% mannitol sc.) and in lowering testosterone among intact male rats (plasma testosterone = 1.64/0.29 ng/mL 6 hrs post 0/3 μg/kg sc.).

UPC:
51184001
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
SML2919-25MG
CAS:
785804-17-3

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