Amino Acid Sequence
Abz-Ser-Asp-Lys-DNP
Application
Abz-SDK(Dnp)P-OH trifluoroacetate is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that specifically binds to the N domain of ACE. Abz-SDK(Dnp)P-OH has been used to study tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells.
Biochem/physiol Actions
Abz-SDK(Dnp)P-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the N domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).
Features and Benefits
This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Molecular Weight: 730.68 (free base basis). Empirical Formula: C31H38N8O13 · xC2HF3O2. Quality Level: 100. Assay: ≥. 91% (HPLC). form: lyophilized powder. solubility: H2O: freely soluble. storage temp.: 2-8°C. SMILES string: OC(: O)C(F)(F)F.Nc1ccccc1C(: O)N[C@@H](CO)C(: O)N[C@@H](CC(O): O)C(: O)N[C@@H](CCCCNc2ccc(cc2[N+]([O-]): O)[N+]([O-]): O)C(: O)N3CCC[C@H]3C(O): O. InChI: 1S/C31H38N8O13.C2HF3O2/c32-19-7-2-1-6-18(19)27(43)36-23(16-40)29(45)35-22(15-26(41)42)28(44)34-21(30(46)37-13-5-9-24(37)31(47)48)8-3-4-12-33-20-11-10-17(38(49)50)14-25(20)39(51)52. 3-2(4,5)1(6)7/h1-2,6-7,10-11,14,21-24,33,40H,3-5,8-9,12-13,15-16,32H2,(H,34,44)(H,35,45)(H,36,43)(H,41,42)(H,47,48). (H,6,7)/t21-,22-,23-,24-. /m0./s1. InChI key: IFSUGURCQHMSJS-JPIABUGISA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51332878
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A5730-1MG