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AC 186 (C09-0729-736)

Aladdin

Catalog No.
C09-0729-736
Manufacturer No.
A288374-50mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $1,285.54
List Price: $1,428.38

product description:AC-186 is a non-steroidal estrogen receptor β (ERβ) agonist (EC50 = 6 nM in a functional assay).1 It is selective for ERβ over ERα (EC50 = 5,000 nM). AC-186 (10 mg/kg) reduces dopaminergic neuronal loss in the substantia nigra,

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product description:AC-186 is a non-steroidal estrogen receptor β (ERβ) agonist (EC50 = 6 nM in a functional assay).1 It is selective for ERβ over ERα (EC50 = 5,000 nM). AC-186 (10 mg/kg) reduces dopaminergic neuronal loss in the substantia nigra, improves novel object recognition, and improves motor performance in male, but not female, rats in a model of Parkinson’s disease induced by 6-OHDA (Item No. 25330). It reduces tactile allodynia in male, but not female or female ovariectomized, rats in a model of spinal nerve ligation-induced neuropathic pain.2 AC-186 (10 and 30 mg/kg) also reduces tactile allodynia in male rats in a model of neuropathic pain induced by paclitaxel. Specifications and Purity: 98%. Molecular Formula: C18H17F3O. Molecular Weight: 306.32. PubChem CID: 71245042. Isomeric SMILES: C1CC(CCC1(C2=CC=C(C=C2)O)C3=CC=CC=C3F)(F)F. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A288374-SCI_9a0f13f7cf4d579f5447091de9e61ac7.pdf
UPC:
12352005
Condition:
New
Availability:
8-12 weeks
Weight:
0.97 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
A288374-50mg
CAS:
1421854-16-1
Product Size:
50mg


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