N-Acetyl-D-Galactosamine Agarose, 5mL resin

Lectins are proteins or glycoproteins that have at least one noncatalytic domain that binds specifically and reversibly to monosaccharides or oligosaccharides. Lectins are important as they are found in applications in science, medicine, agriculture, pharmaceutical companies, biotechnology and other technologies. Some of the possible or ongoing applications of lectins are use as pesticide, fungicide, drug for cancer and antiviral drug. Lectins are used in affinity chromatography for purification of glycoproteins, carbohydrate and glycolipids. Lectins are also useful as markers for blood typing.Therefore purification of lectins is the important. N-Acetyl-D-Galactosamine Agarose is used in purification of N-acetyl-D-galactosamine/ D-galactose specific lectins and carbohydrate binding proteins/enzymes. Examples of N-acetyl-D-galactosamine specific lectins are lectin from Glycine max, Dolichos biflorus, Ricinus communis agglutinin, Peanut agglutinin, Jacalin etc. N-Acetyl-D-Glucosamine agarose and Immobilized D-galactose are also available. Features Ligand : N-acetyl-D-galactosamine Matrix bead structure: 6 % cross-linked agarose Matrix bead size: 45-160mm Matrix activation: Epoxy Matrix binding to ligand : via –OH groups Spacer arm: 12 atoms Binding capacity: ≥ 6 mg lectin from Glycine max/ ml of resin Applications N-Acetyl-D-Galactosamine Agarose is used for purification of N-acetyl-D-galactosamine specific lectins such as lectin from Glycine max and carbohydrate binding proteins/enzymes.