InformationAcotiamide hydrochloride Acotiamide Hydrochloride (YM-443, Z-338) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.In vitroAcotiamide inhibits AChE with half maximal inhibitory concentrations (IC50) of 3.0, 2.3 and 1.2 μM for human recombinant, and rat and canine gastric AChEs, respectively.In vivoAcotiamide is concentrated into the stomach tissue by carrier-mediated uptake processes, which may account for the selective action of acotiamide for gastric smooth muscle but not for skeletal muscle and central nervous system in rats. Specifications and Purity: 99%. Molecular Formula: C21H37ClN4O8S. Molecular Weight: 541.06. PubChem CID: 6918406. Isomeric SMILES: CC(C)N(CCNC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2O)OC)OC)C(C)C.O.O.O.Cl. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A413180-SCI_7b1bcef942e5f0b31e9eba635f33f31d.pdf
- UPC:
- 12352107
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.97 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A413180-250mg
- CAS:
- 773092-05-0
- Product Size:
- 250mg
- Hazard Statement Codes:
- H302:H315:H319
- Precautionary Statement Codes:
- P261:P305+P351+P338
