Adenosine 5'-triphosphate (ATP) Disodium Salt, trihydrate, 2

Adenosine 5'-triphosphate (ATP) disodium salt, trihydrate: Adenosine 5'-triphosphate (ATP) and its phosphate bonds are the basic components of energy exchange in many biological systems. The purification and crystallization of ATP from equine muscle led to the entry of the Sigma Chemical Company into the research biochemical field. Sigma became the first to offer stable, crystalline ATP with a purity approaching 100%. The initial products were isolated from muscle tissue and precipitated with ethanol.1 Currently, this product is isolated from a microbial source and is produced via a fermentation process. No chemical phosphorylation is involved. This ATP has been tested with cell lines to verify the product is not cytotoxic. ATP has intrinsic metal binding affinity. The binding constant for various metals are (given as per mole):2 Mg2+ (9,554), Na+ (13), Ca2+ (3,722), K+ (8), Sr2+ (1,381), Li+ (25).