ADH-1 TRIFLUOROACETATE (C005B-308934)

Catalog No.: C005B-308934
Mfr. No.: SML3469-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $220.37

List Price: $244.85

Biochem/physiol Actions ADH-1 is an N-cadherin (CD325: NCAD) antagonist that selectively inhibits NCAD-dependent neurite outgrowth (IC50 = 323 μ:M: PN1-2 rat cerebral neurons on monolayer of chick NCAD-expressing 3T3), while exhibiting no

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Description
Specifications

Biochem/physiol Actions

ADH-1 is an N-cadherin (CD325; NCAD) antagonist that selectively inhibits NCAD-dependent neurite outgrowth (IC50 = 323 μM; PN1-2 rat cerebral neurons on monolayer of chick NCAD-expressing 3T3), while exhibiting no effect against integrin receptor-dependent neurite outgrowth. ADH-1 inhibits NCAD-mediated signaling events in cultures (0.2-2.5 mg/mL) and exhibits anti-tumor efficacy in vivo (50-100 mg/kg i.p. in rats and mice).

UPC:: 51183702
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3469-10MG
CAS:: 229971-81-7

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