ADP-RIBOSYLCYCLASE

Catalog No.: C15-1213-096
Mfr. No.: A9106-1VL
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: VI

Price: $671.73

List Price: $746.36

Application ADP-ribosylcyclase is a Ca 2+ signaling second messenger. It may be used to study calcium signaling and has been used to research morphine antinociception and tolerance .

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Description
Specifications

Application

ADP-ribosylcyclase is a Ca²⁺ signaling second messenger. It may be used to study calcium signaling and has been used to research morphine antinociception and tolerance .

Biochem/physiol Actions

ADP-ribosylcyclase is an intracellular calcium regulator that cyclizes NAD into cADPR. It is thought that the majority of ADP-ribosylcyclase activity in the brain is linked to CD38. Nicotinamide is a known inhibitor of CD38 ADP-ribosylcyclase activity .

Unit Definition

One unit will produce 1 μmole of cyclic ADP ribose from β-NAD⁺ in 5 minutes at pH 7.0 and 25Ã‚Â°C.

Physical form

Lyophilized powder containing trehalose, potassium phosphate and dithiothreitol

UPC:: 51143206
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: A9106-1VL
CAS:: 135622-82-1

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