ADP-ribosylcyclase

Catalog No.: C15-1213-096
Manufacturer No.: A9106-1VL
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: VI

Price: $596.57

List Price: $662.86

Application ADP-ribosylcyclase is a Ca 2+ signaling second messenger. It may be used to study calcium signaling and has been used to research morphine antinociception and tolerance .

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Description
Specifications

Application

ADP-ribosylcyclase is a Ca²⁺ signaling second messenger. It may be used to study calcium signaling and has been used to research morphine antinociception and tolerance .

Biochem/physiol Actions

ADP-ribosylcyclase is an intracellular calcium regulator that cyclizes NAD into cADPR. It is thought that the majority of ADP-ribosylcyclase activity in the brain is linked to CD38. Nicotinamide is a known inhibitor of CD38 ADP-ribosylcyclase activity .

Unit Definition

One unit will produce 1 μmole of cyclic ADP ribose from β-NAD⁺ in 5 minutes at pH 7.0 and 25Â°C.

Physical form

Lyophilized powder containing trehalose, potassium phosphate and dithiothreitol

UPC:: 12352200
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: A9106-1VL

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