AEM1 (C005B-311933)

Catalog No.: C005B-311933
Mfr. No.: SML1556-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $260.50

List Price: $289.44

Biochem/physiol Actions AEM1 (ARE expression modulator 1) is also a selective inhibitor of sirtuin 2, which is a protein deacetylase mediated by NAD + . Sirtuin 2 supports tumor cell proliferation, thus its inhibition stimulates cell death in

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Biochem/physiol Actions

AEM1 (ARE expression modulator 1) is also a selective inhibitor of sirtuin 2, which is a protein deacetylase mediated by NAD⁺. Sirtuin 2 supports tumor cell proliferation, thus its inhibition stimulates cell death in tumors.

AEM1 is a potent inhibitor of deregulated Nrf2 transcriptional activity. AEM1 broadly decreases the expression of NRF2 controlled genes and sensitizes A549 cells to various chemotherapeutic agents.

UPC:: 51172901
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML1556-5MG
CAS:: 1030123-90-0

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