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aif mouse mab (c09-0739-968)

AIF Mouse mAb (C09-0739-968)

Aladdin

Catalog No.
C09-0739-968
Manufacturer No.
Ab087780-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $3,708.63
List Price: $4,120.70

Mouse anti Human AIF Antibody, Monoclonal(8H1-B10-A12), could be used for WB, IF, ICC and so on .Application:WB: 1/500-1/1000ICC/IF: 1/50-1/200Protein FunctionProbable oxidoreductase that has a dual role in controlling cellular life and death

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Mouse anti Human AIF Antibody, Monoclonal(8H1-B10-A12), could be used for WB, IF, ICC and so on .Application:WB: 1/500-1/1000ICC/IF: 1/50-1/200Protein FunctionProbable oxidoreductase that has a dual role in controlling cellular life and death; during apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e., caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner. Specifications and Purity: mAb(8H1-B10-A12); Mouse anti Human AIF Antibody; WB, IF, ICC; Unconjugated.
UPC:
12352203
Condition:
New
Availability:
8-12 weeks
Weight:
1.09 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
Ab087780-1ml
Product Size:
1ml


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