An Isozyme selective Akt1/2 kinase inhibitor. In in vitro kinase assays, this shows IC|50|= 58 nM, 210 nM, and 2.12 mM for Akt1, Akt2, and Akt3. The inhibition appears to be pleckstrin homology (PH) domain-dependent and the Akt1/2 kinase inhibitor has no inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations as high as 50 µM.Akt1/2 kinase inhibitoris an Isozyme selective Akt1/2 kinase inhibitor. Specification: ≥98% MDL Number: MFCD08705407 Molecular Formula: C36H32F3N7O4•xC2HF3O2 Molecular Weight: 683.69 PubChem CID: 16218954 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A380028-SCI_5b8f56e6e67283efddfa9bc53816f5fd.pdf
- UPC:
- 51111778
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A380028-5mg
- Product Size:
- 5mg
- Precautionary Statement Codes:
- P264
