Aladdin-1

CDK9-IN-7 (compound 21e) is a selective, highly potent, which exhibits more potent over other CDKs (CDK4/cyclinD=148 nM; CDK6/cyclinD=145 nM). CDK9-IN-7 shows antitumor activity without obvious toxicity.

CDI-PEG-CDI

CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 hydrochloride has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN.

CC-671 is a selectively dual inhibitor ofTTK (human protein kinase monopolar spindle 1 [hMps1])andCDC like kinase 2 (CLK2)with IC50s of 5 nM and 3 nM for TTK and CLK2, respectively.

CB1-IN-1

Ceramides comprise spingolipids with acyl chains of C14 to C24 saturated and monounsaturated fatty acids. They are present in most of the mammalian tissues.

C22 Dihydroceramide

Ceramide synthesis is mediated either by the salvage pathway by the acylation of sphingosine or sphingolipids hydrolysis or by de novo pathway via dihydroceramide formation. Structurally, ceramides have a sphingoid base, a long-chain amino...

C12-Sphingosine is a short-chain homologue of Sphingosine. It effectively inhibits the activity of serine palmitoyltransferase in primary cultured cerebellar cells.

Bromosporine对于BRD2，BRD4，BRD9和CECR2的IC50分别为410nM、290nM、122nM和17nM。 Broad spectrum bromodomain inhibitor

Bromoacetamido-dPEG ®₂₄-amido-DBCO is a crosslinker with a bromoacetamido which can react with a free thiol and a DBCO which can be used for a copper-free click" chemistry reaction with an azide group."

Bromo-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.