Aladdin-1

JAMM protease inhibitor

PARP-1 inhibitor; Rac1 inhibitor;

CDK9 Inhibitors

inhibiting collagen production; SRC kinase inhibition; TTX-S channel blockers;

inhibitors of Mycobacterium tuberculosis

antitubercular activity

WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).An...

Sphingosine kinase inhibitors; Sphingosine kinase inhibitors

G protein-coupled receptor GPR132

N-linked glycan biosynthesis modulators

altering the lifespan of eukaryotic organisms; glycogen synthase kinase-3 inhibitors;

Inhibitors of Glycogen Synthase Kinase 3