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ALPHA-HYDROXYMIDAZOLAM-D4100á?G/ML IN METHANOL AMPULE OF 1áML CERTIFIED REFERENCE MATERIAL CERILLIANT

Sigma Aldrich

Catalog No.
C15-1444-390
Manufacturer No.
H-921-1ML
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
ML
Price: $615.03
List Price: $683.37

This internal standard is suitable for midazolam testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, urine drug testing, pain prescription monitoring, or forensic analysis applications. It is an internal standard of

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General description

This internal standard is suitable for midazolam testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, urine drug testing, pain prescription monitoring, or forensic analysis applications.

It is an internal standard of α-hydroxymidazolam, a major metabolite of the benzodiazepine midazolam, formed upon its metabolism by cytochrome P450 3A (CYP3A) isoenzymes.

Application

The Certified Spiking Solution® is suitable for quantitative testing of α-Hydroxymidazolam by HPLC, GC/MS, or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications.

The Certified Reference Material (CRM) in solution can also be used as follows:

  • Liquid chromatography-tandem mass spectrometry (LC–MS/MS) method based determination of 12 psychotropic drugs and their metabolites in guinea pig hair samples
  • Multiresidue analysis of 18 benzodiazepines in human blood and hair samples using LC–MS/MS
  • Detection and estimation of 21 benzodiazepines and three z-drugs from human hair samples after their two-step extraction by LC–MS/MS
  • Simultaneous analysis of 54 benzodiazepine and three z-drug residues from human urine and blood samples by ultra high-performance liquid chromatography- triple quadrupole tandem mass spectrometry (UHPLC-QqQ-MS/MS) method
  • Analysis of 26 compounds, comprising 18 benzodiazepines, seven benzodiazepine metabolites, and one z-drug from dried blood spot (DBS) cards using LC-MS/MS

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

UPC:
51282806
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
H-921-1ML

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