(+)-A-TOCOPHEROL ACETATE ACTIVITY: ~1360 IU/G BIOREAGENT SUITABLE FOR INSECT CELL CULTURE (C005B-302078)

General description

α-Tocopherol acetate is a semisynthetic acetate ester of naturally occurring α-tocopherol.

Application

(+)-α-Tocopherol acetate has been used:

• as a supplement in the human embryonic kidney cells (HEK 293) to assess its impact on cell growth
• as a component of Dulbecco′s Modified Eagle Medium/Nutrient Mixture F-12 (DMEM/F12) for immortalized chondrocyte cell line
• as a component of serum-free medium for human colon tissue organ culture
• to test its antioxidant effects on cow articular chondrocytes

Use in insect cell culture applications as an antioxidant.

Biochem/physiol Actions

α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes.

Caution

Since the M.P. is about 25 °C this preparation is usually an oil. Does not air oxidize.