InformationAmenamevir Amenamevir (ASP2151) is a potent helicase-primase inhibitor and a novel class of antiviral agent.Targetshelicase-primaseIn vitroASP2151 inhibited the in vitro replication of HSV-1. The mean EC50s of ASP2151 against HSV-1 and HSV-2 were 14 (range, 7.7 to 20) and 30 ng/ml (range, 15 to 58), respectively.In vivoIn the cutaneously HSV-1-infected mouse model, ASP2151 dose dependently suppressed intradermal HSV-1 growth, with the effect reaching a plateau at a dose of 30 mg/kg of body weight/day. Specification: 0.98 Molecular Formula: C24H26N4O5S Molecular Weight: 482.55 PubChem CID: 11397521 Isomeric SMILES: CC1=C(C(=CC=C1)C)N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CCS(=O)(=O)CC4 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A413296-SCI_2bca5cb56bddd18871568e9c86d1b142.pdf
- UPC:
- 51342804
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A413296-10mg
- CAS:
- 841301-32-4
- Product Size:
- 10mg
