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amg 548 (c09-0729-869)

AMG 548 (C007B-017281)

Catalog No.
C007B-017281
Mfr. No.
A288830-10mg
Mfr. Name
Aladdin Scientific
Qty/UOM
1
UOM
EA
Price: $440.62
List Price: $489.58

AMG-548, an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >:1000 fold selective against p38γ and p38δ. AMG 548 is also extremely potent in the inhibition of whole blood LPS stimulated

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AMG-548, an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ. AMG 548 is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM)[1]. AMG-548 inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε. Specification: ≥98%(HPLC) Molecular Formula: C29H27N5O Molecular Weight: 461.56 PubChem CID: 11167112 Isomeric SMILES: CN1C(=O)C(=C(N=C1NC[C@H](CC2=CC=CC=C2)N)C3=CC=NC=C3)C4=CC5=CC=CC=C5C=C4 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A288830-SCI_22fb92bbdc8380bcf12f7fa832627fca.pdf
UPC:
51131824
Condition:
New
Availability:
8-12 weeks
Weight:
0.96 Ounces
HazmatClass:
Yes
WeightUOM:
LB
MPN:
A288830-10mg
CAS:
864249-60-5
Health Hazards:
Toxic
Product Size:
10mg
Hazard Statement Codes:
H301:H315:H319:H335
Precautionary Statement Codes:
P261:P264:P270:P271:P280:P301:P321:P330:P337:P302+P352:P304+P340:P305+P351+P338:P362+P364:P405:P403+P233:P501

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