General description
Ammonium acetate (NH4CH3CO2, NH4OAc) is a water-soluble, hygroscopic ammonium salt. It is an eco-friendly and inexpensive compound that can be prepared by reacting glacial acetic acid with ammonia or ammonium carbonate. It is used as a catalyst as well as a source of ammonia in organic synthesis.
Application
Ammonium acetate can be used as a reactant as well as a catalyst in the synthesis of:
- 1,3-oxazine derivatives by three-component condensation reaction with 2-naphthol and aromatic aldehydes.
- Symmetrical terpyridine derivatives by treating with aromatic aldehydes and ethyl cyanoacetate.
- Isoquinolines, furopyridines, and thienopyridines via Pd-catalyzed sequential coupling-imination-annulation reactions of ortho-bromoarylaldehydes and terminal alkynes.
It can also be used as a nitrogen source to synthesize benzoxazole derivatives via multicomponent condensation reaction with catechols, and various aldehydes in the presence of Fe(III)−salen complex as a catalyst.
Features and Benefits
NH4OAc is an eco-friendly, shelf-stable, and safe reagent.
- UPC:
- 12352107
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 238074-25G