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AMPK (ALPHA1/BETA2/GAMMA1) ACTIVE HIS TAGGED HUMAN PRECISIO KINASE RECOMBINANT EXPRESSED IN BACULOVIRUS INFECTED SF9 CELLS (C005B-239060)

Catalog No.
C005B-239060
Mfr. No.
A4611-10UG
Mfr. Name
Sigma-Aldrich
Qty/UOM
10
UOM
UG
Price: $2,751.25
List Price: $3,056.94

Biochem/physiol Actions AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an α catalytic subunit, and non-catalytic β and γ subunits. AMPKs are an important energy-sensing enzyme group in

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Biochem/physiol Actions

AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an α catalytic subunit, and non-catalytic β and γ subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and 3-hydroxy-3-methylglutaryl-CoA reductase. The β subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle.

Physical form

Supplied in 50 mM Sodium Phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

recombinant: expressed in baculovirus infected Sf9 cells. Quality Level: 200. product line: PRECISIO®. Kinase. Assay: ≥. 70% (SDS-PAGE). form: buffered aqueous glycerol solution. specific activity: 297-401 . nmol/min·mg. mol wt: A1 subunit ~68 . kDa, B2 subunit ~36 . kDa, G1 subunit ~40 . kDa. UniProt accession no.: O43741, P54619, Q13131. shipped in: dry ice. storage temp.: −. 70°C. Gene Information: human ... PRKAA1(5562), PRKAB2(5565), PRKAG1(5571). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

Shipping Information:

Dry Ice Surcharge & Ice Pack Shipments: $40

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UPC:
12352204
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
A4611-10UG
Temperature Control Device:
Yes

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