Angiotensinogen (1-14), human (C09-1102-666)

Angiotensinogen (1-14), human is a fragment of the renin substrate angiotensinogen . Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptidesIn VitroAngiotensinogen (AGT) is the only precursor of all angiotensin peptides. Human AGT has 485 amino acids, including a 33 amino-acid signal peptide. The 10 N-terminal amino acids are cleaved by renin to provide angiotensin I (AngI), which is the source for an array of active angiotensin peptides. Angiotensinogen isolated from most species is cleaved by human renin. Synthetic peptides containing the N-terminal amino-acid sequence of angiotensinogen were renin substrates. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Human Endogenous Metabolite. Specification: 0.99 Molecular Formula: C83H122N24O19 Molecular Weight: 1760.01 PubChem CID: 16168596 Isomeric SMILES: CCC(C)C(C(=O)NC(CC1=CNC=N1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CNC=N4)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(CC5=CNC=N5)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)O)N